For Large Dogs Many pets are maintained long-term on every-other-day or every-third-day administration.

Does my dog have to take Denamarin for life?

How long should my dog take Denamarin? Your vet will be able to advise you on what is best for your pet. Some conditions, such as acute liver toxicity (poisoning) may only need a few weeks of treatment, whereas longer-term diseases may require ongoing medication.

What are the long term side effects of Denamarin in dogs?

Denamarin has no known side-effects. Your veterinarian can evaluate the length of support needed through follow-up examinations, blood work and/or other laboratory work. At home, watch for a response in your pet's attitude, appetite, and activity level.

What if I forgot to give my dog Denamarin?

Speak with your veterinarian if you forget to give a dose of Denamarin® or milk thistle/SAMe. Generally, they may recommend that you give it when you remember, or, if it is almost time for your next dose, to skip the missed dose and resume your normal dosing schedule.

Can Denamarin be broken in half?

Denamarin tablets are enteric-coated to protect them from being oxidised. They must therefore be fed whole (do not split or crumble the tablets). Tablets should be given on an empty stomach at least one hour before a meal for optimum absorption (an overnight fast is preferred).

Can you give Denamarin every other day?

Can I give Denamarin every other day?

For Large Dogs

Many pets are maintained long-term on every-other-day or every-third-day administration.

Should Denamarin be given morning or night?

Where possible we recommend an overnight fast to ensure the stomach is empty before administering the tablet, thereby allowing the best absorption of the active ingredients. However, when an overnight fast is not possible please allow a minimum of 2 hours (ideally longer) after feeding before administering the tablets.

What happens if I give my dog Denamarin with food?

While you should always give your pet the medication on an empty stomach, this also has shown to have no major adverse reactions. If you happen to forget and your dog does have foods prior to taking the medicine, it will just lower the effectiveness.

Does Denamarin suppress appetite in dogs?

This supplement seems to be very well tolerated. Occasionally, it seems to cause a decreased appetite in some dogs, but this is very rare. If possible, it is best given on an empty stomach.

Can you give too much Denamarin?

Denamarin is a very safe medication/supplement to give even at high doses like that.

How to know if Denamarin is working?

How will I know if Denamarin is helping my pet? Your vet is likely to recommend follow‑up examinations and blood tests to check on how Denamarin is helping to improve your pet's liver function. At home, watch for improvements in attitude, appetite and activity level.

What is a good substitute for Denamarin?

Denamarin is a combination of an anti oxidant called SAMe, which can be found online and in stores, and marin, the active ingredient in milk thistle. You could try a combination of milk thistle (about 1/4th of the labeled dose for a person) and SAMe (around 225 mg).

Is milk thistle as good as Denamarin?

The specific silybin used in Denamarin has been shown to provide better bioavailability in dogs and cats compared to the standardised milk thistle commonly available in health food stores and over-the-counter in pharmacies. Provides comprehensive liver support with two active ingredients SAMe and Silybin.

How safe is Denamarin for dogs?

Are there any side effects? There are no known side effects, and Denamarin's active ingredients have been shown to be well tolerated by both dogs and cats, with a wide margin of safety.

How long can an old dog live with high liver enzymes?

Some dogs have mild liver disease that progresses slowly and remains relatively stable over months, or even years. Other dogs may have a rapid progression of liver failure. And they may only live for weeks, or even days, following their diagnosis.

Does Denamarin help dogs' kidneys?

Commercial companies produce Denamarin and Denosyl (labeled as kidney mixes containing SAM-e and Silybin) as supplements for pets. SAM-e is used to replace the amino acids lost due to kidney disease, and Silybin is an extract of milk thistle thought to work as an antioxidant and an anti-inflammatory.

Are there any side effects to Denamarin?

Denamarin® Advanced Tablets have no known serious side-effects. If your pet is using this medication for the first time please watch for any allergic reactions that might occur, if your pet develops a rash, etc call your veterinarian immediately. If you notice anything unusual, contact your veterinarian.

What happens if a human takes Denamarin?

Most likely nothing will happen after taking the Denamarin. You can read more about S -Adenosylmethionine here.

What's the difference between Denamarin and Denamarin Advanced?

Denamarin® Advanced Chewable Tablets is a liver supplement for dogs or cats and provides greater overall absorption as compared to original Denamarin salt. This translates into smaller, fewer tablets, and a lower cost at all weight ranges.

How long should a dog stay on Denamarin?

How long can my dog stay on denamarin? This depends on the current condition of your dog. These tablets are safe for long term use. We recommend consulting a veterinarian for accurate feeding regimes based on your dog's health.

Should Denamarin be given at night or morning?

Ideally Denamarin should be given first thing in the morning after a fast overnight, and then wait at least an hour to give anything else.

Can you break up Denamarin?

The Denamarin tablets should be kept in their original packaging until used and should not be crushed or split (ie, you should not split larger doses formulated for dogs to give to a cat).

Does Denamarin increase urination?

Denamarin is not expected to cause an increase in urination.

Can you give a dog too much Denamarin?

Thankfully, overdoses of this product are unlikely to cause significant morbidity (severity of symptoms). Gastrointestinal effects as evidenced by inappetence, vomiting and/or diarrhea may be seen but shouldn't need to be treated.

Can I give Denamarin with other meds?

While no drug interactions have been documented, in theory, Denamarin® Advanced may have an effect on: Tramadol, dextromethorphan, meperidine, selegiline, fluoxetine, amitriptyline, clomipramine and other antidepressant medications, warfarin, verapamil, diazepam.

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