Ted DeSalvo, from Windham, Ohio, suddenly lost his beloved three-year-old boxer Greta after she had to be euthanized following intense seizures on June 2 - a day after she took Simparica Trio medication. The chewable tablet is for dogs and cats to help protect against ticks, fleas and heartworm disease.

What is the death rate for Simparica Trio?

When examining the Food and Drug Administration (FDA), Adverse Reactions (AR) reports for active ingredients of a common class, the data in Table 2 show that spinosad containing treatments (Comfortis® and Trifexis®) resulted in a combined 363,295 AR reports with 11,478 deaths, followed by afoxolaner treatments (Nexgard ...

Does Simparica Trio harm dogs?

Simparica may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders. Simparica has not been evaluated in pregnant, breeding or lactating dogs. The most common adverse reactions in clinical trials were vomiting and diarrhea.

How many dogs get seizures from Simparica Trio?

There are 720 reported seizures for Bravecto in four years, 557 for Simparica in three years, and six seizures for Credelio in the first six months after is was approved. The manufacturers says the risk of side effects is very rare, less than one in 10,000 doses sold.

What are the hazards of Simparica Trio?

May be harmful if swallowed. However, ingestion is not likely to be a primary route of occupational exposure. Direct contact with eyes may cause temporary irritation. Exposure may cause temporary irritation, redness, or discomfort.

[Warning] Flea and Tick Product Side Effects

Should I not give my dog Simparica trio?

Use with caution in dogs with a history of seizures. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders.

What is the FDA warning against Simparica Trio?

Sarolaner, one of the ingredients in SIMPARICA TRIO, is a member of the isoxazoline class. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures.

What is the Simparica Trio controversy?

The medication can cause ataxia, tremors, and seizures from the ingredient in the tablet, Sarolaner. Owners that have dogs with a history of seizures or neurologic disorders are told to use Simparica Trio with caution.

What is the safest flea and tick medication for dogs?

Our Vet Pick: Best in Show

Our vets agree Simparica is the best overall flea and tick medication for stopping fleas and ticks that latch onto your dog. Many of our veterinarians use Simparica® on their own pets.

Which is safer, NexGard or Simparica?

Both products are safe for dogs when following directions and have been approved by the FDA to treat and prevent flea and tick infestations. While Simparica was trialed and not approved, Nexgard has not yet been evaluated for use in breeding, pregnant, or lactating dogs.

How do I detox my dog from Simparica Trio?

If you're unable to visit a vet, there are a few at-home remedies you can try in order to help reduce the effects of the Simparica, such as monitoring their diet, providing plenty of rest and hydration, and providing supplements like probiotics and omega-3 fatty acids.

What precautions should be taken during Simparica trio?

Keep away from children and animals. The safe use of SIMPARICA TRIO has not been evaluated in breeding, pregnant, or lactating dogs. Prior to administration of SIMPARICA TRIO dogs should be tested for existing heartworm infections.

Are dogs getting sick from Simparica Trio?

In a third field safety and effectiveness study, SIMPARICA TRIO was administered to 120 dogs with roundworms. Adverse reactions in dogs treated with SIMPARICA TRIO included diarrhea and vomiting.

What age is Simparica Trio safe?

DESCRIPTION SIMPARICA TRIO (sarolaner, moxidectin, and pyrantel chewable tablets) is a flavored, chewable tablet for administration to dogs 8 weeks of age and older.

How long does Simparica Trio stay in a dog's system?

How long does Simparica protection last? Simparica is a monthly chewable that starts protecting in hours* and lasts for 35 days. That gives you a little wiggle room at the end of the month, in case you're late with the next month's dose.

How common are seizures from Simparica Trio?

The overall global reporting rate for any clinical sign reported for Simparica Trio (including vomiting, lethargy, diarrhea, or any neurological sign) is classified as “very rare,” which is defined by international regulatory authorities as less than 1 report per 10,000 doses administered.

Should you give your dog Simparica trio?

It's a parasite-preventative medication approved by the FDA for dogs. However, like any medication, there can be side effects. Here's a breakdown: Safe for Most Dogs: When used as directed by a veterinarian, Simparica Trio is generally safe and effective for most dogs.

Can a dog overdose on Simparica Trio?

In the overdose groups, transient and self-limiting neurological signs were observed in some animals: mild tremors at 3 times the maximum exposure dose and convulsions at 5 times the maximum exposure dose. All dogs recovered without treatment.

Has Simparica Trio killed dogs?

Ever since, the controversy around these products has been increasing on a continuous basis. Both of these drugs already have quite an impressive legacy of suspicion of causing extremely serious adverse reactions, including the death of several hundred of innocent Canine victims.

How many dogs have died from flea treatment?

CBC Marketplace has discovered that more than 2,000 animals are reported to have died in North America since 2008 as a result of exposure to flea and tick treatment products, which can contain dangerous chemicals that kill fleas but can also harm pets.

What flea medicine makes dogs sick?

Active ingredients found in common flea and tick medications include naturally derived pyrethrins, synthetic pyrethroids, or a newer class of drugs, isoxazolines, which were the first oral flea and tick products. While they are all highly effective, they can cause toxicity if given incorrectly or if an overdose occurs.

Which is safer Heartgard or Simparica?

Simparica is safe for use in dogs ages 6 months and up, and Heartgard Plus can be administered to puppies from the age of 6 weeks. Heartgard Plus is also safe for use in breeding or pregnant female dogs, while Simparica has not been evaluated for safe use in breeding, pregnant, or lactating dogs.

What is the safest flea treatment for dogs?

If chemical products are necessary for additional flea or tick control, NRDC recommends s-methoprene or pyriproxyfen, which are less toxic ingredients—but read the labels carefully because some products use them with other, more harmful pesticides.

Which is safer, Simparica Trio or Bravecto?

Both products are safe for dogs when following directions and have been approved by the FDA to treat and prevent flea and tick infestations. However, unlike Bravecto, Simparica has yet to be approved for use in breeding, pregnant, or lactating dogs.

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