What are the possible side effects of Denamarin?

Denamarin has no known side-effects. Your veterinarian can evaluate the length of support needed through follow-up examinations, blood work and/or other laboratory work. At home, watch for a response in your pet's attitude, appetite, and activity level.
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What are the long term side-effects of Denamarin in dogs?

There are no known side effects, and Denamarin's active ingredients have been shown to be well tolerated by both dogs and cats, with a wide margin of safety. Can Denamarin be used with other products? Yes, your vet may recommend combining Denamarin with other products or dietary changes.
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How long should a dog stay on Denamarin?

How long should my dog take Denamarin? Your vet will be able to advise you on what is best for your pet. Some conditions, such as acute liver toxicity (poisoning) may only need a few weeks of treatment, whereas longer-term diseases may require ongoing medication.
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What happens if I give my dog Denamarin with food?

While you should always give your pet the medication on an empty stomach, this also has shown to have no major adverse reactions. If you happen to forget and your dog does have foods prior to taking the medicine, it will just lower the effectiveness.
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What drugs interact with Denamarin?

While no drug interactions have been documented, in theory, Denamarin® Advanced Tablets may have an effect on: Tramadol, dextromethorphan, meperidine, selegiline, fluoxetine, amitriptyline, clomipramine and other antidepressant medications, warfarin, verapamil, diazepam.
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Nutramax Denamarin Liver Health Supplement for Dogs, With S-Adenosylmethionine (SAMe)

Should Denamarin be given morning or night?

Where possible we recommend an overnight fast to ensure the stomach is empty before administering the tablet, thereby allowing the best absorption of the active ingredients. However, when an overnight fast is not possible please allow a minimum of 2 hours (ideally longer) after feeding before administering the tablets.
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Does Denamarin affect appetite?

Occasionally, it seems to cause a decreased appetite in some dogs, but this is very rare. If possible, it is best given on an empty stomach. Skorupski, K.A., et al. Prospective Randomized Clinical Trial Assessing the Efficacy of Denamarin for Prevention of CCNU-Induced Hepatopathy in Tumor-Bearing Dogs.
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Can dogs have water with Denamarin?

Denamarin tablets are not to be broken up. Administer the nearest whole tablet dose or use a combination of sizes. Always give tablets on an empty stomach, at least one hour before feeding. Following the tablet, administer a few mls of water to help the tablet reach the stomach.
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Can I give Denamarin every other day?

For Large Dogs

Many pets are maintained long-term on every-other-day or every-third-day administration.
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What if I forgot to give my dog Denamarin?

Speak with your veterinarian if you forget to give a dose of Denamarin® or milk thistle/SAMe. Generally, they may recommend that you give it when you remember, or, if it is almost time for your next dose, to skip the missed dose and resume your normal dosing schedule.
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Can you break up Denamarin?

Denamarin tablets are enteric-coated to protect them from being oxidised. They must therefore be fed whole (do not split or crumble the tablets). Tablets should be given on an empty stomach at least one hour before a meal for optimum absorption (an overnight fast is preferred).
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Are elevated liver enzymes in dogs serious?

A lot of times, the increase in liver enzymes is mild and self-limiting; rarely, it can indicate a serious underlying liver disease. Which of the lab values are the liver enzymes? The main liver enzymes that your veterinarian may look at include the ALT (alanine aminotransferase) and ALP (alkaline phosphatase).
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Is there an alternative to Denamarin?

Denamarin is a combination of an anti oxidant called SAMe, which can be found online and in stores, and marin, the active ingredient in milk thistle. You could try a combination of milk thistle (about 1/4th of the labeled dose for a person) and SAMe (around 225 mg).
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Does Denamarin increase urination?

Denamarin is not expected to cause an increase in urination.
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Does Denamarin really work for dogs?

Denamarin is the number one veterinarian recommended liver support brand. It combines the power of S-Adenosylmethionine (SAMe) and Silybin to help support healthy liver function in dogs and cats.
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Can you give too much Denamarin?

Denamarin is a very safe medication/supplement to give even at high doses like that.
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Does Denamarin have side effects?

Denamarin® Advnaced has no known serious side-effects. If your pet is using this medication for the first time please watch for any allergic reactions that might occur, if your pet develops a rash, etc call you veterinarian immediately. If you notice anything unusual, contact your veterinarian.
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Can I give my dog Denamarin at night?

The liver does most of its cleanup at night, so this gives it a boost. You should not give Denamarin and milk thistle at the same time, as they may interfere with each other's absorption and effectiveness. So you could give Denamarin in the morning and milk thistle at night or give them at least 3 hours apart.
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Is Denamarin an anti inflammatory?

It is most effective where applied locally because it attracts white blood cells to promote healing. It is also absorbed through the skin and provides relief to any inflammation, including joints. Denamarin – is usually used to improve liver function but has also been shown to help with senility.
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What happens if a human takes Denamarin?

Most likely nothing will happen after taking the Denamarin. You can read more about S -Adenosylmethionine here.
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Can milk thistle reverse liver damage in dogs?

Milk Thistle May Help Reverse Liver Damage

It can help protect your dog's liver from heavy toxicity, which will damage it over time. This is because milk thistle helps remove toxins from your dog's body by flushing them out of the liver and reducing the strain on the liver.
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What's the difference between Denamarin and Denamarin Advanced?

Denamarin® Advanced Chewable Tablets is a liver supplement for dogs or cats and provides greater overall absorption as compared to original Denamarin salt. This translates into smaller, fewer tablets, and a lower cost at all weight ranges.
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Why can't you crush Denamarin?

As long as you mix and give your pup the crushed denamarin right away, this will not affect the stability of the tablet. If you were to crush the tablet/capsule, then try to store the crushed pieces, then this would definitely affect the stability of the medication.
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Does Denamarin interact with other medications?

While no drug interactions have been documented, in theory, Denamarin® may have an effect on: Tramadol, dextromethorphan, meperidine, selegiline, fluoxetine, amitriptyline, clomipramine and other antidepressant medications, warfarin, verapamil, diazepam.
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Is there a liquid form of Denamarin?

There isn't a liquid form of Denamarin unfortunately.
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